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Protein Information

Protein Name Cup2p
Description Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations; required for regulation of copper genes in response to DNA-damaging reagents; CUP2 has a paralog, HAA1, that arose from the whole genome duplication
Aminoacid Sequence
Download FASTA 
>CUP2 YGL166W
MVVINGVKYACETCIRGHRAAQCTHTDGPLQMIRRKGRPSTTCGHCKELRRTKNFNPSGG
CMCASARRPAVGSKEDETRCRCDEGEPCKCHTKRKSSRKSKGGSCHRRANDEAAHVNGLG
IADLDVLLGLNGRSSDVDMTTTLPSLKPPLQNGEIKADSIDNLDLASLDPLEQSPSISME
PVSINETGSAYTTTNTALNDIDIPFSINELNELYKQVSSHNSHSQ* 
Transcription Factor
Binding site(s)		 HTHNNGCTGD
GCGTCTTTTCCGCTGA
TCTTTTGCTG
TCTTTTTGCTG
TCTTTTTTGCTG
Regulon See Venn diagram regulon   
Documented targets See documented regulated genes
Potential targets See potential regulated genes (Attention! Can return hundreds of genes)
External source Open in SGD external link
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