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Protein Information
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Protein Name |
Fkh1p |
Description |
Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching |
Aminoacid Sequence
Download FASTA
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>FKH1 YIL131C
MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYA
KIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNL
ESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDY
CLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDV
NPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENR
YIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKA
FEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIP
APESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNN
SSLS* |
Transcription Factor Binding site(s) |
GTMAACAA
RTAAAYAA
RYMAAYA
RYAAACAWW
aaDtGTAAACAAagxxga
gtaaAcAaa
AAACA
GTAAACAA
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Regulon |
See Venn diagram regulon |
Documented targets |
See documented regulated genes |
Potential targets |
See potential regulated genes
(Attention! Can return hundreds of genes) |
External source |
Open in SGD |
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