Yeastract IST IBB-BSRG INESC-ID
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Protein Information

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Protein Name Gis1p
Description JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain
Aminoacid Sequence
Download FASTA
>YDR096W GIS1
MEIKPVEVIDGVPVFKPSMMEFANFQYFIDEITKFGIENGIVKVIPPKEWLELLEGSPPA
ESLKTIQLDSPIQQQAKRWDKHENGVFSIENEYDNKSYNLTQWKNLAESLDSRISQGDFN
DKTLKENCRVDSQQDCYDLAQLQILESDFWKTIAFSKPFYAVDENSSIFPYDLTLWNLNN
LPDSINSSNRRLLTGQSKCIFPWHLDEQNKCSINYLHFGAPKQWYSIPSANTDQFLKILS
KEPSSNKENCPAFIRHQNIITSPDFLRKNNIKFNRVVQFQHEFIITFPYCMYSGFNYGYN
FGESIEFILDQQAVVRKQPLKCGCGNKKEERKSGPFSNLSYDSNESEQRGSITDNDNDLF
QKVRSFDELLNHSSQELQNLEDNKNPLFSNINMNRPQSSSLRSTTPNGVNQFLNMNQTTI
SRISSPLLSRMMDLSNIVEPTLDDPGSKFKRKVLTPQLPQMNIPSNSSNFGTPSLTNTNS
LLSNITATSTNPSTTTNGSQNHNNVNANGINTSAAASINNNISSTNNSANNSSSNNNVST
VPSSMMHSSTLNGTSGLGGDNDDNMLALSLATLANSATASPRLTLPPLSSPMNPNGHTSY
NGNMMNNNSGNGSNGSNSYSNGVTTAAATTTSAPHNLSIVSPNPTYSPNPLSLYLTNSKN
PLNSGLAPLSPSTSNIPFLKRNNVVTLNISREASKSPISSFVNDYRSPLGVSNPLMYSST
INDYSNGTGIRQNSNNINPLDAGPSFSPLHKKPKILNGNDNSNLDSNNFDYSFTGNKQES
NPSILNNNTNNNDNYRTSSMNNNGNNYQAHSSKFGENEVIMSDHGKIYICRECNRQFSSG
HHLTRHKKSVHSGEKPHSCPRCGKRFKRRDHVLQHLNKKIPCTQEMENTKLAES* 
Transcription Factor
Binding site(s)
TWAGGGAT
AGGGG
ttAGGGGt
See documented regulated genes
See potential regulated genes (Attention! Can return hundreds of genes)
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