S.cerevisiae - Yeastract

Protein Information

Protein Name	Hap1p
Description	Zinc finger transcription factor; involved in the complex regulation of gene expression in response to levels of heme and oxygen; localizes to the mitochondrion as well as to the nucleus; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus
Aminoacid Sequence Download FASTA	>HAP1 YLR256W MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPLHMSSDSSKIKRKRNRI PLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELKKLRER VKSLEKTLSKVHSSPSSNSLKSYNTPESSNLFMGSDEHTTLVNANTGSASSASHMHQQQQ QQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLTKDFDLLHIKSNGTIHLGATHWL SIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKLKSSKCPINHAQAPPSAAAAATRKC PVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSGMIPPREDTSSQKRCPVDHTMYSAGMM PPKDETPSPFSTKAMIDHNKHTMNPPQSKCPVDHRNYMKDYPSDMANSSSNPASRCPIDH SSMKNTAALPASTHNTIPHHQPQSGSHARSHPAQSRKHDSYMTESEVLATLCEMLPPKRV IALFIEKFFKHLYPAIPILDEQNFKNHVNQMLSLSSMNPTVNNFGMSMPSSSTLENQPIT QINLPKLSDSCNLGILIIILRLTWLSIPSNSCEVDLGEESGSFLVPNESSNMSASALTSM AKEESLLLKHETPVEALELCQKYLIKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDL TTLTNTNNTGMANPGHDSESHQILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSN NGSKKANPSTNPTLNNNMSAATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKI WYYIVSMDVNQSLSLGSPRLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQID LCIIAVLNHILNVSLARSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGG SVDSNNDEIYGLPKLPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKH MTIRMLLYLLNYILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNT NSLFDYMNVILSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVE DEDVKVKQESSDELKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMN KSTGFFVSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDAL GFVSPTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAK RRRFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITS QMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMNMN GAGTANTDTSANGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINPSSLV EVVGGYNDPNNLGRNDAVDFLPVDNVEIDGVGIKINYHLLTSIYVTSILSYTVLEDDAND EK*
Transcription Factor Binding site(s)	CGGN{3}TANCGG CGGN{6}CGG CGGN{3}TANCGGN{3}TA TCGCGTTCATATATATCGGATATACTCTTGAGGCACAATT CGCATTTATCGC CCGaTAaHtCCGG tAWcTCCG TCGGCCGA CCGNTATNTCC CCGATA CCGXTATXTCC GGCCGAT TCCGATA TCCGATATA TCCGATAAC TCCGATAAA GGNGATAA GGCGATAT GGCGATAA GGCCGATAAC GCCGATATA GCCGATAT GCCGATAAA GCCGATA GCCGAT GACCGATAT GACCGATAAA GACCGATA GACCGA CNGATTG CGATAT CGATAAA CCNANAAC CCGATAAA ANCGATAT ANCGATAAA ANCGATA ACCGATAAC ACCGATA ACCGAT ACCGANA ACCGAAATA ACCGATAA ACCGATAAA ACCGATAT ANCGATAA ANCGATATA ATNTCCG CCGAAAT CCGAAATA CCGATAA CCGATAG CCGATAT CCGATTG CGATATA CNGAAAT GCCGATAA GCCGATAAC GCCGATAG GCCGATTG GCCGNTAAA GCNGANAT GGCCGATAA GGCCGATAAA GGCCGATAG GGCGATAAA GGCGATATA GGNGATA GNCGNTAA TCCGAT TCCGATAG TCCGATAT GACCGANA GACCGAAAT CGATAA CCGNTANA ACCGATTG ACCGATATA ACCGATAG TCCGATTG TCCGATAA GCCGNTA GACCGAT
Regulon	See Venn diagram regulon
Documented targets	See documented regulated genes
Potential targets	See potential regulated genes (Attention! Can return hundreds of genes)
External source	Open in SGD