Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Protein Information

Protein Name Ixr1p
Description Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication
Aminoacid Sequence
Download FASTA 
>IXR1 YKL032C
MNTGISPKQDDASNSNLLNIGQDHSLQYQGLEHNDSQYRDASHQTPHQYLNQFQAQPQQQ
QQQQQQQQQQQQQAPYQGHFQQSPQQQQQNVYYPLPPQSLTQPTSQSQQQQQQQQQQQYA
NSNSNSNNNVNVNALPQDFGYMQQTGSGQNYPTINQQQFSEFYNSFLSHLTQKQTNPSVT
GTGASSNNNSNNNNVSSGNNSTSSNPAQLAASQLNPATAAAAAANNAAGPASYLSQLPQV
QRYYPNNMNALSSLLDPSSAGNAAGNANTATHPGLLPPNLQPQLTHHQQQMQQQLQLQQQ
QQLQQQQQLQQQHQLQQQQQLQQQHHHLQQQQQQQQHPVVKKLSSTQSRIERRKQLKKQG
PKRPSSAYFLFSMSIRNELLQQFPEAKVPELSKLASARWKELTDDQKKPFYEEFRTNWEK
YRVVRDAYEKTLPPKRPSGPFIQFTQEIRPTVVKENPDKGLIEITKIIGERWRELDPAKK
AEYTETYKKRLKEWESCYPDENDPNGNPTGHSHKAMNMNLNMDTKIMENQDSIEHITANA
IDSVTGSNSNSTNPNTPVSPPISLQQQPLQQQQQQQQQQQHMLLADPTTNGSIIKNE* 
Transcription Factor
Binding site(s)		 KTTSAAYKGTTYASA
Regulon See Venn diagram regulon   
Documented targets See documented regulated genes
Potential targets See potential regulated genes (Attention! Can return hundreds of genes)
External source Open in SGD external link
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