S.cerevisiae - Yeastract

Protein Information

Protein Name	Leu3p
Description	Zinc-knuckle transcription factor, repressor and activator; regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; acts as a repressor in leucine-replete conditions and as an activator in the presence of alpha-isopropylmalate, an intermediate in leucine biosynthesis that accumulates during leucine starvation
Aminoacid Sequence Download FASTA	>LEU3 YLR451W MEGRSDFVATSQSGSEMSHSETRNRTGMNARKRKFACVECRQQKSKCDAHERAPEPCTKC AKKNVPCILKRDFRRTYKRARNEAIEKRFKELTRTLTNLTSDEILKKIEEEQEIVLDNSN FTKEKVKQLRKSAFETTEIEPRSYKTLRGEPISYSTNRRHTDSSPLTLLSSSTNFDPVHS TNVMTDDQLKCLPKSLGDVYLSSSDIAELFQEFATKYHQFLPVVDLSKGAERIYHLSPCL FWVILLIGLRRKFGATDLMTRLSVLVKSVLSEITISPIIRYTPSDKDEPVLNVASVYSVQ AFLLYTFWPPLTSSLSADTSWNTIGTAMFQALRVGLNCAGFSKEYASANSELVNEQIRTW ICCNVVSQTVASSFGFPAYVSFDYLVISSIRVPNSKSQVDIPNELRQMAQIARFENQIVN TMNSTPASVTGMVSQEEKQPLLHVLNQQLSQLEISLEENNLDDIRKFLLLVAKVHLLTYY FTDVTSQSAGKSNGNIYEGSYSIMELDTSFETKRGLVKVYNAAVNFLIHANSMWEHDPTI IKYFPGLFVLNIWQSACIISKLIHSSLHSMLDVNSGKKAYNNAISLTFNASVLKYDMAYR SSGIMRSIWSLFANMYDAWKNDQKEGGGRLNNDFNLGITIKSRMSVNVFFDCLYILKEKC GMAKLERETKVSTAYNVDEEEEEDEDEEGEEEEEEEELSSKVPENMDSQQLRTRKFTNVR HPEKKARKIIETIPLDPNPINAGSTSSGSSLTTPNSQVANTISYRGILNKMSPREQLNHA NLDSSVSTDIKDTEAVNEPLPIGRNAEHPANQPPLSITQMQENTLPATQANSSLLETYPI VQSNPVTTTIKESPNSIMAGWDNWESDMVWRDVDILMNEFAFNPKV*
Transcription Factor Binding site(s)	CCGN{4}CGG CCGGNNCCGG CCGTTAACGG acCGG HtagxxtWCgCCGGTHxtDxa CCGGAAC TCGCCGGTCCCG TCCGGTAGCAA TTAACGG TCGCCGGTTT TCGCCGG TCCGTTACCG TCCGTTAC TCCGGTACCG GTCCGGTAGC GGGCNGGT GGCCCGGTTCCG GGCCCGGAAC GCGGAAT GCCGGTTCCG GCCGGTACCG GCAGAAC CTGCCGGTA CTGCCGG CCTGTTCC CCGTTTCCG CCGTTTC CCGTTANCG CCGTTANC CCGTTACCGG CCGTTAC CCGGTCCCG CCGGTCCC CCGGTAGC CCGGCCC CCCGGTTT GTTGCCGGTAC GCCGGTTT CTGCCGGT CCTGTTC CCCGCTCC ACCGTTACCGGA
Regulon	See Venn diagram regulon
Documented targets	See documented regulated genes
Potential targets	See potential regulated genes (Attention! Can return hundreds of genes)
External source	Open in SGD