Yeastract IST INESC-ID IBB-BSRG
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Protein Information

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Protein Name Rph1p
Description JmjC domain-containing histone demethylase; specifically demethylates H3K36 tri- and dimethyl modification states; associates with actively transcribed (RNA polymerase II) regions in vivo and specifically targets H3K36 in its trimethylation state as its substrate; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway
Aminoacid Sequence
Download FASTA
>YER169W RPH1
MTKLIAPSEIVGGVPVFKPTYEQFEDFYAYCKAINKYGMKSGVVKVIPPKEWKDKLDLPY
SAETLQKIKIKSPIQQHISGNKGLFMVQNVEKNKTYNIIQWKDLSKDYVPPEDPKARRNS
RKGSVSKSTKLKLKNFESSFNIDDFEQFRTEYTIDLSDFQNTERLKFLEEYYWKTLNFTT
PMYGADTPGSIFPEGLNVWNVAKLPNILDHMETKVPGVNDSYLYAGLWKASFSWHLEDQD
LYSINYIHFGAPKQWYSIPQEDRFKFYKFMQEQFPEEAKNCPEFLRHKMFLASPKLLQEN
GIRCNEIVHHEGEFMITYPYGYHAGFNYGYNLAESVNFALEEWLPIGKKAGKCHCISDSV
EIDVKKLAKSWRDNNKESKGTPPLNQLPNPAMPLLHRPTLKEMESSSLRSTSPDVGHFSN
FKSKSSGVSSPLLSRMKDYSNIVEPTLEDPTLKLKRISSFQEQPLNKLLKRETSQTAMLT
DHEDNIVAMSLTSMANSAASSPRLPLSRLNSSNELSNAQPLLDMTNNTLAFPRPNGPSGL
NPLLYISNKNISGISHSAPHSPVNPNISLIKRVKSPNIVTLNISRESSRSPIALNYEARQ
QHSQQHSFSTPSTVSNLSTSVLGPLSDTNDIKTPHPERPNHKTANRILKKESPVETSKSN
LILSKVASTRQEDSFTSRNDDLDKEQGSSPLNSKFAPEEIVLSGKNKIYICKECQRKFSS
GHHLTRHKKSVHSGEKPHSCPKCGKRFKRRDHVLQHLNKKIPCISNETTVDAPIMNPTVQ
PQDGKAAINQQSTPLN* 
Transcription Factor
Binding site(s)
CCCCT
ttagggg
aaxxxDaWTtAGGGGKgxa
tWAGGGGt
RxgYxxt
AGGGG
See regulon   
See documented regulated genes
See potential regulated genes (Attention! Can return hundreds of genes)
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