S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Hac1p	YCL043C	PubMed Kawahara T et al., Mol Biol Cell, 1997 Oct;8(10):1845-62	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	SC medium; mid-log phase
		PubMed Mori K et al., J Biol Chem, 1998 Apr 17;273(16):9912-20	Direct	EMSA	N/A	S288c	N/A
		PubMed Kimata Y et al., Genes Cells, 2006 Jan;11(1):59-69	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	Non-stressed vs tunicamycin (TM)-treated (2 microg/mL, 1 h) wt (WT) cells and cells harboring HAC1i mutation (HAC1u cells (Ire1-HAC1 pathway completely blocked) vs HAC1i cells (Ire1-HAC1 pathway constitutively activated) cultured without extrinsic ER stress)
		PubMed Van Dalfsen KM et al., Dev Cell, 2018 Jul 16;46(2):219-235.e8	Indirect	RNA-seq - wt vs TF mutant	Positive	BrUn1362	Tunicamycin
			Indirect	RNA-seq - wt vs TF mutant	Positive	BrUn1362	5mM DTT
			Indirect	Ribo-seq: WT vs TF mutant	Positive	BrUn1362	Tunicamycin
			Indirect	Ribo-seq: WT vs TF mutant	Positive	BrUn1362	5mM DTT