S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Hac1p	YJL034W	PubMed Cox JS et al., Cell, 1996 Nov 1;87(3):391-404	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	tunicamycin treatment
		PubMed Nikawa J et al., Nucleic Acids Res, 1996 Nov 1;24(21):4222-6	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	tunicamycin treatment
		PubMed Kawahara T et al., Mol Biol Cell, 1997 Oct;8(10):1845-62	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	SC medium; mid-log phase
		PubMed Mori K et al., J Biol Chem, 1998 Apr 17;273(16):9912-20	N/A		N/A	S288c	N/A
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Kimata Y et al., Genes Cells, 2006 Jan;11(1):59-69	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	Non-stressed vs tunicamycin (TM)-treated (2 microg/mL, 1 h) wt (WT) cells and cells harboring HAC1i mutation (HAC1u cells (Ire1-HAC1 pathway completely blocked) vs HAC1i cells (Ire1-HAC1 pathway constitutively activated) cultured without extrinsic ER stress)
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Hou J et al., FEMS Yeast Res, 2014 May;14(3):481-94	Indirect	Microarray analysis - wt vs TF mutant	Negative	S288c	DTT inhibition
		PubMed Pincus D et al., Proc Natl Acad Sci U S A, 2014 Oct 14;111(41):14800-5	Indirect	RNA-seq - wt vs TF overexpression	Positive	S288c	DTT and Tunicamycin
		PubMed Lee YM et al., Environ Microbiol, 2017 Feb;19(2):584-597	Indirect	lacZ - wt vs TF mutant	Positive	BY4741	2 mM DTT for 2 hours
		PubMed Van Dalfsen KM et al., Dev Cell, 2018 Jul 16;46(2):219-235.e8	Indirect	RNA-seq - wt vs TF mutant	Positive	BrUn1362	Tunicamycin
			Indirect	RNA-seq - wt vs TF mutant	Positive	BrUn1362	5mM DTT
			Indirect	Ribo-seq: WT vs TF mutant	Positive	BrUn1362	Tunicamycin
			Indirect	Ribo-seq: WT vs TF mutant	Positive	BrUn1362	5mM DTT