S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Hap4p	YHR051W	PubMed Trawick JD et al., Mol Cell Biol, 1992 May;12(5):2302-14	Direct	lacZ - wt vs mutant promoter sequence	Positive	S288c	2% lactate 100mg/mL of b-aminolevulinic acid
		PubMed Trawick JD et al., J Biol Chem, 1989 Apr 25;264(12):7005-8	N/A		N/A	S288c	N/A
		PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Workman CT et al., Science, 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Schuurmans JM et al., FEMS Yeast Res, 2008 Feb;8(1):26-34	Indirect	Microarray analysis - wt vs TF mutant	Positive	CEN.PK113-7D	wt versus Tf overexpression 0.67 %YNB, 2% glucose and 0.1 M phtalic acid pH 5 30.C mid exp cells
		PubMed Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Imamura Y et al., PLoS One, 2015 Jun 18;10(6):e0130397	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	YPEG (1% yeast extract, 2% peptone, 3% EtOH, 3% Glycerol)
		PubMed Holland P et al., Nucleic Acids Res, 2019 Jun 4;47(10):4986-5000	Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in anaerobic glucose limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in ethanol limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in respiratory glucose limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h