S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Hsf1p	YGR142W	PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Yamamoto A et al., J Biol Chem, 2005 Mar 25;280(12):11911-9	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium 39ºC (heat shock)
		PubMed Workman CT et al., Science, 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Eastmond DL et al., J Biol Chem, 2006 Oct 27;281(43):32909-21	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303-1A	Cells grown in YPAD at 30.C to mid-log phase (A600 of 0.5) submitted to heat-shock (37.C, 15 min)
		PubMed Yamamoto A et al., Eukaryot Cell, 2007 Aug;6(8):1373-9	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Diamide
		PubMed Hou J et al., FEMS Yeast Res, 2014 May;14(3):481-94	Indirect	Microarray analysis - wt vs TF overexpression	Positive	S288c	DTT inhibition
		PubMed Cho BR et al., Mol Microbiol, 2014 Jul;93(2):306-16	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Grown to early exponential phase, andthen incubated in the presence of 10% ethanol
		PubMed SolÃs EJ et al., Mol Cell, 2016 Jul 7;63(1):60-71	Indirect	Net-seq	Positive	S288c	basal conditions
		PubMed de Jonge WJ et al., EMBO J, 2017 Feb 1;36(3):274-290	Direct	ChIP	N/A	S288C	SC medium
		PubMed de Jonge WJ et al., EMBO J, 2017 Feb 1;36(3):274-290	Indirect	RT-PCR - wt vs TF mutant	Negative	S288C	SC medium
		PubMed Pincus D et al., Mol Biol Cell, 2018 Dec 15;29(26):3168-3182	Direct	ChIP-seq	N/A	BY4741	YPDA (with 0.002% adenine), non-heat shock, 5Â´heat shock and 120Â´heat shock
			Direct	ChIP-seq	N/A	BY4741	YPDA (with 0.002% adenine) Rapamycin (1 microM), non-heat shock
			Direct	ChIP-seq	N/A	BY4741	YPDA (with 0.002% adenine), 5' heat shock
			Indirect	NAC-seq (nascent mRNA-sequencing)	Positive	BY4741	YPDA (with 0.002% adenine) Rapamycin (1 microM), non-heat shock
			Indirect	NAC-seq (nascent mRNA-sequencing)	Positive	BY4741	YPDA (with 0.002% adenine), 5' heat shock
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C