S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Ino4p	YJL153C	PubMed Hirsch JP et al., Mol Cell Biol, 1986 Oct;6(10):3320-8	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	cells grown in 10 mM inositol; synthetic medium
		PubMed Klig LS et al., Proc Natl Acad Sci U S A, 1984 Jun;81(12):3816-20	Indirect	Western blot - wt vs TF mutant	Positive	S288c	cells were grown in 50 uM inositol
		PubMed Donahue TF et al., J Biol Chem, 1981 Jul 10;256(13):7077-85	N/A		N/A	S288c	N/A
		PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Hoppen J et al., Yeast, 2005 Jun;22(8):601-13	Indirect	lacZ - wt vs TF mutant	Positive	JS91.15-9	Depressing conditions: 5 microM . inositol +5 microM choline
		PubMed Hoppen J et al., Yeast, 2005 Jun;22(8):601-13	Indirect	lacZ - wt vs TF mutant	Positive	JS91.15-9	Repressing conditions: 200 microM inositol +2mM choline
		PubMed Workman CT et al., Science, 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Ernst J et al., Mol Syst Biol, 2007;():Ernst J et al., Mol Syst Biol, 2007;():	Direct	Chip-on-chip	N/A	S288c	SCD medium + amino acid starvation
		PubMed Shetty A et al., Eukaryot Cell, 2010 Dec;9(12):1845-55	Direct	ChIP	N/A	S288c	Without Inositol and Cholin
		PubMed Gururaj C et al., J Biol Chem, 2013 Jul 12;288(28):20453-63	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Inositol depletion
		PubMed Chumnanpuen P et al., BMC Syst Biol, 2013;():	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Steady-state aerobic chemostat 30.C
		PubMed Zhu X et al., Genetics, 2015 Oct;201(2):525-42	Indirect	RNA-seq - wt vs TF mutant	Positive	S288c	YPA
		PubMed Bergenholm D et al., mSystems, 2018 Jul-Aug;3(4):	Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state aerobic chemostat cultivation at 30 .C in nitrogen-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state aerobic chemostat cultivation at 30 .C in glucose-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state chemostat cultivation at 30 .C in oxygen- and glucose-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state aerobic chemostat cultivation at 30 .C in ethanol-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
		PubMed Holland P et al., Nucleic Acids Res, 2019 Jun 4;47(10):4986-5000	Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in anaerobic glucose limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in ethanol limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in nitrogen limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in respiratory glucose limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C