S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Pho4p	YBR093C	PubMed Vogel K et al., Mol Cell Biol, 1989 May;9(5):2050-7	Direct	DNA footprinting	N/A	S288c	N/A
		PubMed Barbaric S et al., Mol Cell Biol, 1998 May;18(5):2629-39	Indirect	lacZ - wt vs TF mutant	Positive	S288c	phosphate starvation; cells grown in phosphate-free synthetic medium
		PubMed Ogawa N et al., Mol Biol Cell, 2000 Dec;11(12):4309-21	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Exponential phase cells cultivated in YPD
		PubMed Moreno-Herrero F et al., Biochem Biophys Res Commun, 2001 Jan 12;280(1):151-7	Direct	EMSA	N/A	S288c	N/A
		PubMed Terrell AR et al., J Biol Chem, 2002 Aug 23;277(34):31038-47	Direct	EMSA	N/A	S288c	Phosphate depletion
		PubMed Neef DW et al., Mol Cell Biol, 2003 Jun;23(11):3788-97	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF mutant	Positive	N/A	Cells grown in synthetic medium supplemented with 2% dextrose
			Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Nishizawa M et al., Eukaryot Cell, 2008 Jun;7(6):949-57	Direct	ChIP	N/A	S288c	low Pi (SD medium supplemented only with 0.2 uM sodium Pi)
		PubMed Nishizawa M et al., PLoS Biol, 2008 Dec 23;6(12):2817-30	Direct	Chip-on-chip	N/A	S288c	YNB medium without phosphate + 0,2microM (low Pi; phosphate limitation)
		PubMed He Y et al., Mol Microbiol, 2012 Jan;83(2):395-407	Direct	ChIP	N/A	S288c	low phosphate medium no inositol and choline
		PubMed Aow JS et al., Nucleic Acids Res, 2013 May;41(9):4877-87	Direct	ChIP	N/A	S288c	low phosphate
		PubMed He et al., Elife, 2017;6(0):e25157He et al., Elife, 2017;6(0):e25157	Indirect	RNA-seq - wt vs TF mutant	Positive	EY0057 pho80DELTA	EY0057 pho80DELTA; Minimal medium; mid-log phase
		PubMed Gurvich Y et al., PLoS Biol, 2017 Dec 13;15(12):e2002039	Indirect	RNA-seq - wt vs TF mutant	Positive	BY4741	BY4741; SC medium; Phosphate(i) starvation condition; 30.C; mid-log phase
			Indirect	RNA-seq - wt vs TF mutant	Positive	BY4741 PHO4SA12346 allele	BY4741 PHO4SA12346 allele ; SC medium; Low P(i) concentration; 30.C; mid-log phase