S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Zap1p	YKL175W	PubMed MacDiarmid CW et al., EMBO J, 2000 Jun 15;19(12):2845-55	Indirect	lacZ - wt vs TF overexpression	Positive	S288c	zinc-replete medium (SD + 2 µM ZnCl2)
		PubMed Lyons TJ et al., Proc Natl Acad Sci U S A, 2000 Jul 5;97(14):7957-62	Indirect	Microarray analysis - wt vs TF mutant	Positive	DY1457	Exponential cells grown in synthetic defined medium + zinc
		PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Wu CY et al., J Biol Chem, 2007 Jan 26;282(4):2184-95	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	zinc depletion
		PubMed Wu CY et al., BMC Genomics, 2008;():Wu CY et al., BMC Genomics, 2008;():	Indirect	Microarray analysis - wt vs TF overexpression	Positive	S288c	SD medium + 2% galactose + 1 Î¼M ZnCl2
		PubMed Frey AG et al., J Biol Chem, 2011 Feb 25;286(8):6844-54	Indirect	lacZ - wt vs TF mutant	Positive	S288c	LZM (Low Zinc Medium) + 3microM ZnCl2
		PubMed Tatip S et al., Mol Microbiol, 2020 Jan;113(1):285-296	Indirect	RT-PCR - wt vs. TF mutant	Positive	BY4743	LZM + 1 microM ZnCl2
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C