S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rfa1p
Description	Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; role in DNA catenation/decatenation pathway of chromosome disentangling; relocalizes to the cytosol in response to hypoxia
GO Terms: Biological Process	level 3: meiotic cell cycle level 4: reciprocal meiotic recombination level 4: establishment of protein localization level 6: DNA replication level 6: DNA topological change level 6: heteroduplex formation level 6: DNA repair level 6: DNA recombination level 7: telomere maintenance via recombination level 7: positive regulation of DNA helicase activity level 7: telomere maintenance via telomere lengthening level 7: nucleotide-excision repair level 7: mitotic recombination level 8: telomere maintenance via telomerase level 8: double-strand break repair via homologous recombination level 8: protein ubiquitination level 8: DNA unwinding involved in DNA replication level 9: positive regulation of endodeoxyribonuclease activity
GO Terms: Molecular Function	level 4: nucleic acid binding level 5: DNA binding level 5: metal ion binding level 6: damaged DNA binding level 6: double-stranded DNA binding level 6: sequence-specific DNA binding level 6: single-stranded DNA binding level 6: mRNA binding level 7: zinc ion binding level 8: single-stranded telomeric DNA binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 4: DNA replication factor A complex level 4: chromosome, telomeric region level 5: nucleus level 6: condensed nuclear chromosome
External source	Open in SGD