S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Alg3p
Description	Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; involved in synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins; G353A missense mutation in human ortholog ALG3 implicated in carbohydrate deficient glycoprotein syndrome type IV, which is characterized by microcephaly, severe epilepsy, minimal psychomotor development, partial deficiency of sialic acids in serum glycoproteins; wild-type human ALG3 can complement yeast alg3 mutant
GO Terms: Biological Process	level 4: mannosylation level 5: protein glycosylation level 5: oligosaccharide-lipid intermediate biosynthetic process
GO Terms: Molecular Function	level 3: transferase activity level 4: glycosyltransferase activity level 5: mannosyltransferase activity level 7: dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
GO Terms: Cellular Component	level 3: membrane level 4: endoplasmic reticulum level 4: integral component of membrane level 5: endoplasmic reticulum membrane
External source	Open in SGD