S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Mec1p
Description	Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres
GO Terms: Biological Process	level 3: meiotic cell cycle level 4: reciprocal meiotic recombination level 5: chromatin organization level 5: cellular response to DNA damage stimulus level 6: DNA replication level 6: DNA repair level 6: DNA damage checkpoint signaling level 6: DNA recombination level 6: protein phosphorylation level 6: telomere maintenance level 6: DNA damage induced protein phosphorylation level 6: phosphorylation level 7: positive regulation of cellular respiration level 7: telomere maintenance via recombination level 9: positive regulation of DNA-templated DNA replication
GO Terms: Molecular Function	level 3: transferase activity level 4: nucleotide binding level 4: protein kinase activity level 5: protein serine/threonine kinase activity level 5: kinase activity level 6: ATP binding
GO Terms: Cellular Component	level 4: mitochondrion level 5: nucleus
External source	Open in SGD