S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Gdt1p
Description	Calcium and manganese transporter with higher affinity for Ca2+; involved in Ca2+ and Mn2+ homeostasis; localizes to the cis- and medial-Golgi apparatus; GFP-fusion localizes to the vacuole; required for the Mn2+-dependent function of glycosylation enzymes; TMEM165, a human ortholog linked to Congenital Disorders of Glycosylation, functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression regulated by Gcr1p
GO Terms: Biological Process	level 7: calcium ion transmembrane transport level 7: manganese ion transmembrane transport level 8: cellular calcium ion homeostasis level 9: cellular manganese ion homeostasis level 9: Golgi calcium ion homeostasis level 9: Golgi calcium ion transport
GO Terms: Molecular Function	level 6: metal ion transmembrane transporter activity level 7: calcium ion transmembrane transporter activity level 8: manganese ion transmembrane transporter activity
GO Terms: Cellular Component	level 3: membrane level 4: integral component of membrane level 4: vacuole level 4: Golgi apparatus level 5: cis-Golgi network level 5: Golgi membrane level 5: vacuolar membrane level 6: Golgi medial cisterna level 6: fungal-type vacuole level 7: fungal-type vacuole membrane
External source	Open in SGD