Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Npc2p
Description Sterol transport protein and functional homolog of human NPC2/He1; acts with Ncr1p in sterol trafficking; human NPC2 is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes; yeast NPC2 can complement mutations in human NPC2
GO Terms:
Biological Process		 level 5: lipid transport external link
level 6: intracellular sterol transport external link
level 6: sterol transport external link
GO Terms:
Molecular Function		 level 4: phosphatidylserine binding external link
level 4: phosphatidylcholine binding external link
level 5: sterol binding external link
level 5: phosphatidylinositol binding external link
GO Terms:
Cellular Component		 level 4: vacuole external link
level 6: fungal-type vacuole external link
level 6: fungal-type vacuole lumen external link
External source Open in SGD external link
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