S.cerevisiae - Yeastract

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Gene Ontology Information

Protein Name	Yfh1p
Description	Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog FXN is mutated in Friedrich's ataxia; human FTL gene can complement yeast yfh1 null mutant
GO Terms: Biological Process	level 5: iron-sulfur cluster assembly level 5: glutathione metabolic process level 5: heme biosynthetic process level 5: ion transport level 6: iron incorporation into metallo-sulfur cluster level 9: cellular iron ion homeostasis level 10: iron ion homeostasis
GO Terms: Molecular Function	level 3: oxidoreductase activity level 4: iron chaperone activity level 5: 2 iron, 2 sulfur cluster binding level 6: ferroxidase activity level 8: ferrous iron binding level 8: ferric iron binding
GO Terms: Cellular Component	level 4: mitochondrion level 5: mitochondrial matrix
External source	Open in SGD

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