S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Cdc34p
Description	Ubiquitin-conjugating enzyme (E2); catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation; protein abundance increases in response to DNA replication stress; human CDC34 functionally complements the thermosensitivity of the cdc34-2 mutant
GO Terms: Biological Process	level 3: cell division level 3: cell cycle level 5: G2/M transition of mitotic cell cycle level 6: DNA replication level 7: proteasome-mediated ubiquitin-dependent protein catabolic process level 8: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process level 8: ubiquitin-dependent protein catabolic process level 8: protein ubiquitination level 9: protein polyubiquitination level 9: protein autoubiquitination
GO Terms: Molecular Function	level 3: transferase activity level 4: nucleotide binding level 5: ubiquitin-protein transferase activity level 6: ATP binding level 6: ubiquitin protein ligase activity level 6: ubiquitin conjugating enzyme activity
GO Terms: Cellular Component	level 3: cytoplasm level 5: nucleus level 6: SCF ubiquitin ligase complex
External source	Open in SGD