S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	San1p
Description	Ubiquitin-protein ligase; involved in proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition; prefers a window of exposed hydrophobicity that causes a particular level of protein insolubility, suggesting that San1p evolved to target highly aggregation-prone proteins
GO Terms: Biological Process	level 5: response to misfolded protein level 7: nuclear protein quality control by the ubiquitin-proteasome system level 8: ubiquitin-dependent protein catabolic process level 8: protein ubiquitination
GO Terms: Molecular Function	level 5: metal ion binding level 5: ubiquitin-protein transferase activity level 6: ubiquitin protein ligase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cytoplasm level 5: peroxisome level 5: nucleus
External source	Open in SGD