S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ref2p
Description	RNA-binding protein; involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes; putative regulatory subunit of type 1 protein phosphatase Glc7p, required for actomyosin ring formation, and for timely dephosphorylation and release of Bnr1p from the division site; relocalizes to the cytosol in response to hypoxia
GO Terms: Biological Process	level 5: regulation of protein localization to cell division site involved in cytokinesis level 7: mRNA processing level 8: mRNA 3'-end processing level 8: positive regulation of mitotic actomyosin contractile ring assembly level 9: termination of RNA polymerase II transcription, poly(A)-coupled level 9: sno(s)RNA 3'-end processing level 11: negative regulation of mRNA polyadenylation
GO Terms: Molecular Function	level 3: chromatin binding level 5: RNA binding
GO Terms: Cellular Component	level 3: cytosol level 5: nucleus level 5: mRNA cleavage and polyadenylation specificity factor complex
External source	Open in SGD