S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ubp3p
Description	Ubiquitin-specific protease that cleaves Ub-protein fusions; interacts with cofactor Bre5p to regulate transport between ER and Golgi, deubiquitinating COPII and COPI proteins, Sec23p and Sec27p; mediates steady-state retention of Golgi membrane proteins with Bre5p; phosphorylation (S695) by Hog1p regulates transcriptional activation by osmostress; inhibits Ras/PKA signaling through Ira2p; inhibits silencing; role in ribophagy; protein abundance increases in response to DNA replication stress
GO Terms: Biological Process	level 5: proteolysis level 5: protein retention in Golgi apparatus level 6: regulation of response to osmotic stress level 6: regulation of ER to Golgi vesicle-mediated transport level 7: protein deubiquitination level 7: ribophagy level 8: ubiquitin-dependent protein catabolic process
GO Terms: Molecular Function	level 3: hydrolase activity level 4: peptidase activity level 5: cysteine-type peptidase activity level 6: mRNA binding level 6: cysteine-type endopeptidase activity level 6: cysteine-type deubiquitinase activity
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 3: Ubp3-Bre5 deubiquitination complex level 5: nucleus
External source	Open in SGD