Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Cdc4p Description
F-box protein required for both the G1/S and G2/M phase transitions; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCFCdc4 complex; SCFCdc4 acts as a ubiquitin-protein ligase directing ubiquitination of cyclin-dependent kinase (CDK) phosphorylated substrates, such as: Sic1p, Far1p, Cdc6p, Clb6p, and Cln3p
GO Terms:
level 3: cell cycle cell division meiotic cell cycle sporulation resulting in formation of a cellular spore G2/M transition of mitotic cell cycle G1/S transition of mitotic cell cycle SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process protein ubiquitination endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO Terms:
level 5: ubiquitin-protein transferase activity ubiquitin binding phosphoserine residue binding ubiquitin protein ligase activity U3 snoRNA binding GO Terms:
level 3: nuclear matrix 90S preribosome nucleus nucleolus nuclear SCF ubiquitin ligase complex SCF ubiquitin ligase complex External source
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