S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rog3p
Description	Alpha-arrestin involved in ubiquitin-dependent endocytosis; contributes to desensitization of agonist-occupied alpha-factor receptor Ste2p by Rsp5p-independent internalization; PPXY motif-mediated binding of the ubiquitin ligase Rsp5p is not required for adaptation; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; SWAT-GFP and mCherry fusion proteins localize to the cytosol; ROG3 has a paralog, ROD1, that arose from the whole genome duplication
GO Terms: Biological Process	level 5: protein transport level 6: ubiquitin-dependent endocytosis level 7: adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion level 8: positive regulation of receptor internalization
GO Terms: Molecular Function	level 3: protein-macromolecule adaptor activity level 6: ubiquitin protein ligase binding
GO Terms: Cellular Component	level 3: cytosol level 3: cytoplasm level 4: plasma membrane
External source	Open in SGD