S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Erg26p
Description	C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; human homolog NSDHL implicated in CK syndrome, and can complement yeast null mutant; molecular target of natural product and antifungal compound FR171456
GO Terms: Biological Process	level 4: lipid metabolic process level 5: steroid metabolic process level 6: steroid biosynthetic process level 6: ergosterol biosynthetic process level 6: sterol biosynthetic process
GO Terms: Molecular Function	level 3: oxidoreductase activity level 5: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor level 6: 3-beta-hydroxy-delta5-steroid dehydrogenase activity level 6: sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity level 6: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity level 6: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity level 6: C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
GO Terms: Cellular Component	level 3: membrane level 4: endoplasmic reticulum level 5: endoplasmic reticulum membrane
External source	Open in SGD