S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rai1p
Description	Nuclear decapping endonuclease; targets mRNAs with unmethylated 7-methylguanosine cap structures and 5'-triphosphates; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; involved in an early step of decapping nicotinamide adenine dinucleotide (NAD) capped nuclear NAD-RNAs; relocalizes to the cytosol in response to hypoxia; homologous to human DOM3Z
GO Terms: Biological Process	level 4: regulation of catalytic activity level 6: nucleic acid phosphodiester bond hydrolysis level 7: DNA-templated transcription termination level 7: rRNA processing level 7: mRNA processing level 7: deadenylation-independent decapping of nuclear-transcribed mRNA level 8: NAD-cap decapping level 8: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 8: nuclear-transcribed mRNA catabolic process level 9: nuclear polyadenylation-dependent rRNA catabolic process level 9: cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 9: maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 9: termination of RNA polymerase II transcription, poly(A)-coupled
GO Terms: Molecular Function	level 3: hydrolase activity level 3: enzyme regulator activity level 4: nucleotide binding level 5: RNA binding level 5: mRNA 5'-diphosphatase activity level 5: nuclease activity level 5: metal ion binding level 8: phosphodiesterase decapping endonuclease activity
GO Terms: Cellular Component	level 3: cytosol level 5: nucleus
External source	Open in SGD