S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Kar2p
Description	ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p
GO Terms: Biological Process	level 3: karyogamy involved in conjugation with cellular fusion level 4: protein refolding level 4: endoplasmic reticulum unfolded protein response level 5: response to unfolded protein level 5: chaperone cofactor-dependent protein refolding level 6: cellular response to unfolded protein level 6: SRP-dependent cotranslational protein targeting to membrane, translocation level 6: post-translational protein targeting to membrane, translocation level 7: ubiquitin-dependent ERAD pathway level 7: fungal-type cell wall beta-glucan biosynthetic process level 7: protein localization to endoplasmic reticulum
GO Terms: Molecular Function	level 2: protein folding chaperone level 3: hydrolase activity level 3: ATP hydrolysis activity level 3: ATP-dependent protein folding chaperone level 4: unfolded protein binding level 4: nucleotide binding level 4: misfolded protein binding level 4: heat shock protein binding level 6: ATP binding
GO Terms: Cellular Component	level 3: membrane level 3: cytoplasm level 4: endoplasmic reticulum chaperone complex level 4: endoplasmic reticulum level 4: luminal surveillance complex level 5: nucleus level 5: endoplasmic reticulum lumen
External source	Open in SGD