S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Iml1p
Description	GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of the SEA complex, a coatomer-related complex that associates dynamically with the vacuole; Iml1p functions in the SEACIT complex as a GAP for the Rag family GTPase Gtr1p (EGOC subunit), resulting in the inhibition of TORC1 signaling in response to amino acid deprivation; the Iml1p/SEACIT complex is required for non-nitrogen-starvation (NNS)-induced autophagy
GO Terms: Biological Process	level 4: intracellular signal transduction level 5: cellular response to oxidative stress level 5: protein transport level 7: positive regulation of GTPase activity level 7: regulation of autophagosome assembly level 8: negative regulation of TOR signaling level 8: negative regulation of small GTPase mediated signal transduction level 8: positive regulation of autophagy level 9: negative regulation of TORC1 signaling
GO Terms: Molecular Function	level 5: GTPase activator activity
GO Terms: Cellular Component	level 3: Seh1-associated complex level 3: GATOR1 complex level 3: membrane level 4: vacuole level 5: vacuolar membrane level 6: extrinsic component of fungal-type vacuolar membrane level 7: fungal-type vacuole membrane
External source	Open in SGD