S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ypf1p
Description	Intramembrane aspartyl protease of the perinuclear ER membrane; acts in a branch of ER-associated degradation (ERAD) that degrades functional proteins rather than misfolded proteins; regulates abundance of high-affinity plasma membrane transporters, such as Ctr1p and Zrt1p, during the starvation response; has a presenilin fold; member of the GxGD family of intramembrane proteases; closest human homolog is signal peptide peptidase (SPP)
GO Terms: Biological Process	level 5: proteolysis level 5: cellular response to starvation level 6: membrane protein proteolysis level 6: proteolysis involved in protein catabolic process level 6: signal peptide processing
GO Terms: Molecular Function	level 3: hydrolase activity level 4: peptidase activity level 6: aspartic-type endopeptidase activity level 7: aspartic endopeptidase activity, intramembrane cleaving
GO Terms: Cellular Component	level 3: membrane level 4: integral component of membrane level 4: endoplasmic reticulum level 4: perinuclear endoplasmic reticulum membrane level 5: endoplasmic reticulum membrane level 6: integral component of cytoplasmic side of endoplasmic reticulum membrane level 6: integral component of lumenal side of endoplasmic reticulum membrane
External source	Open in SGD