S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sac1p
Description	Phosphatidylinositol phosphate phosphatase; role in early and medial Golgi PtdIns4P hydrolysis; regulated by Vps74p interaction; ER localized transmembrane protein which cycles through the Golgi; role in protein trafficking, processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis by modulating PtdIns(4)P metabolism; PtdIns4P PPase activity is crucial for autophagosome-vacuole fusion during autophagy; human homolog SACM1L complements autophagy defects of the null
GO Terms: Biological Process	level 6: autophagosome-lysosome fusion level 7: phosphatidylinositol dephosphorylation
GO Terms: Molecular Function	level 3: hydrolase activity level 6: phosphatase activity level 9: phosphatidylinositol-3-phosphatase activity level 9: phosphatidylinositol-4-phosphate phosphatase activity level 10: phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
GO Terms: Cellular Component	level 3: membrane level 4: integral component of membrane level 4: mitochondrion level 4: endoplasmic reticulum level 4: Golgi apparatus level 5: Golgi membrane level 5: cortical endoplasmic reticulum level 5: endoplasmic reticulum membrane level 6: Golgi medial cisterna level 6: integral component of Golgi membrane level 6: integral component of endoplasmic reticulum membrane level 6: mitochondrial outer membrane level 6: SPOTS complex level 7: host cell viral assembly compartment
External source	Open in SGD