S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Emg1p
Description	Methyltransferase for rRNA; methylates pseudouridine 18S rRNA residue 1191; member of the SPOUT methyltransferase family; required for maturation of 18S rRNA and for 40S ribosomal subunit production independent of methyltransferase activity; forms homodimers; human ortholog is mutated in Bowen-Conradi syndrome, and equivalent yeast mutation affects Emg1p dimerization and localization but not methyltransferase activity; human EMG1 complements lethality of null and ts mutant
GO Terms: Biological Process	level 3: methylation level 6: ribosome biogenesis level 6: ribosomal small subunit biogenesis level 7: rRNA processing level 7: rRNA base methylation level 9: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 9: endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 9: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO Terms: Molecular Function	level 3: transferase activity level 5: RNA binding level 5: methyltransferase activity level 6: rRNA binding level 7: rRNA (pseudouridine) methyltransferase activity
GO Terms: Cellular Component	level 3: nuclear periphery level 3: cytoplasm level 3: ribonucleoprotein complex level 5: 90S preribosome level 5: small-subunit processome level 5: nucleus level 5: nucleolus level 6: nuclear microtubule
External source	Open in SGD