S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Arv1p
Description	Cortical ER protein; implicated in the membrane insertion of tail-anchored C-terminal single transmembrane domain proteins; may function in transport of glycosylphosphatidylinositol intermediates into the ER lumen; required for normal intracellular sterol distribution; human ARV1, required for normal cholesterol and bile acid homeostasis, can complement yeast arv1 null mutant; human variant causing early onset epileptic encephalopathy is unable to rescue the yeast null
GO Terms: Biological Process	level 4: lipid metabolic process level 5: sterol metabolic process level 5: sphingolipid metabolic process level 5: lipid transport level 5: regulation of plasma membrane sterol distribution level 6: sphingolipid biosynthetic process level 6: intracellular sterol transport level 6: ER to Golgi ceramide transport level 6: endocytosis level 7: GPI anchor biosynthetic process level 7: sterol import
GO Terms: Molecular Function	level 7: zinc ion binding
GO Terms: Cellular Component	level 3: membrane level 4: endoplasmic reticulum level 4: Golgi apparatus level 4: integral component of membrane level 5: endoplasmic reticulum membrane level 5: cortical endoplasmic reticulum level 5: Golgi membrane
External source	Open in SGD