S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Spt5p
Description	Spt4p/5p (DSIF) transcription elongation factor complex subunit; the Spt4/5 complex binds to ssRNA in a sequence-specific manner, and in concert with RNAP I and II has multiple roles regulating transcriptional elongation, RNA processing, quality control, and transcription-coupled repair; interacts with DNA upstream of RNAPII and the non-template strand of the transcription bubble; Spt5p is the only transcription elongation factor conserved in all domains of life
GO Terms: Biological Process	level 5: intracellular mRNA localization level 6: chromatin remodeling level 7: mRNA processing level 7: spliceosomal complex assembly level 7: regulation of rRNA processing level 7: regulation of DNA-templated transcription level 8: regulation of transcription by RNA polymerase II level 8: transcription elongation by RNA polymerase II promoter level 8: regulation of DNA-templated transcription elongation level 8: positive regulation of autophagy level 9: regulation of transcription-coupled nucleotide-excision repair level 10: positive regulation of transcription elongation by RNA polymerase I level 10: positive regulation of transcription elongation by RNA polymerase II level 10: negative regulation of transcription elongation by RNA polymerase I
GO Terms: Molecular Function	level 3: protein-containing complex binding level 4: histone binding level 5: DNA binding level 5: snRNP binding level 6: RNA polymerase II complex binding level 6: RNA polymerase I general transcription initiation factor binding level 6: single-stranded RNA binding level 6: mRNA binding level 6: rRNA binding level 7: U5 snRNA binding level 7: RNA polymerase I core binding level 7: U6 snRNA binding level 7: U1 snRNA binding level 7: U2 snRNA binding level 7: U4 snRNA binding
GO Terms: Cellular Component	level 3: chromatin level 4: mitochondrion level 5: DSIF complex level 5: rDNA heterochromatin level 5: nucleus level 5: chromosome
External source	Open in SGD