S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sub1p
Description	Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4)
GO Terms: Biological Process	level 5: hyperosmotic response level 7: regulation of DNA-templated transcription level 8: double-strand break repair via nonhomologous end joining level 8: negative regulation of ascospore formation level 8: regulation of transcription by RNA polymerase II level 8: termination of RNA polymerase II transcription level 9: RNA polymerase III preinitiation complex assembly level 9: positive regulation of transcription by RNA polymerase II level 9: positive regulation of transcription by RNA polymerase III level 10: positive regulation of transcription initiation by RNA polymerase II level 10: positive regulation of transcription elongation by RNA polymerase II
GO Terms: Molecular Function	level 3: chromatin binding level 4: transcription coactivator activity level 5: DNA binding level 6: G-quadruplex DNA binding
GO Terms: Cellular Component	level 3: transcription regulator complex level 5: nucleus
External source	Open in SGD