Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Nfi1p
Description SUMO E3 ligase; catalyzes sumoylation of Yku70p/80p and Sir4p promoting telomere anchoring to the nuclear envelope and regulating telomerase activity; DNA-bound form catalyzes a DNA-damaged triggered sumoylation wave resulting in multisite modification of several DNA repair proteins, enhancing interactions between these proteins and accelerating repair; sumoylates Cse4p, a prerequisite for STUbL-mediated Ub-dependent degradation; role in telomere length maintenance
GO Terms:
Biological Process		 level 3: chromosome segregation external link
level 5: DNA double-strand break attachment to nuclear envelope external link
level 8: protein sumoylation external link
GO Terms:
Molecular Function		 level 3: transferase activity external link
level 5: SUMO transferase activity external link
level 5: metal ion binding external link
level 6: double-stranded DNA binding external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component		 level 3: chromatin external link
level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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