S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Isw2p
Description	ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth; exhibits basal levels of chromatin binding throughout the genome as well as interacts with sequence-specific factors to accurately position nucleosomes in chromatin; targeted by Ume6p- and Sua7p-dependent DNA looping to many loci genome-wide
GO Terms: Biological Process	level 5: chromatin organization level 6: chromatin remodeling level 6: rDNA heterochromatin formation level 8: termination of RNA polymerase II transcription level 8: subtelomeric heterochromatin formation level 9: positive regulation of transcription by RNA polymerase II level 9: negative regulation of transcription by RNA polymerase II level 9: negative regulation of antisense RNA transcription
GO Terms: Molecular Function	level 3: ATP-dependent activity, acting on DNA level 3: chromatin binding level 3: hydrolase activity level 3: helicase activity level 4: DNA translocase activity level 4: nucleosome binding level 4: nucleotide binding level 4: ATP-dependent chromatin remodeler activity level 5: DNA binding level 6: single-stranded DNA binding level 6: ATP binding level 8: centromeric DNA binding
GO Terms: Cellular Component	level 4: chromosome, telomeric region level 5: nucleus level 6: CHRAC level 6: nuclear microtubule
External source	Open in SGD