Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Ncr1p
Description Vacuolar membrane protein involved with Npc2p in sterol trafficking; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p
GO Terms:
Biological Process		 level 4: lipid metabolic process external link
level 5: sphingolipid metabolic process external link
level 5: lipid transport external link
level 6: sterol transport external link
GO Terms:
Molecular Function		 level 5: sterol binding external link
GO Terms:
Cellular Component		 level 3: membrane external link
level 4: vacuole external link
level 4: endoplasmic reticulum external link
level 4: integral component of membrane external link
level 5: vacuolar membrane external link
level 7: fungal-type vacuole membrane external link
External source Open in SGD external link
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