S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Taz1p
Description	Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant
GO Terms: Biological Process	level 4: lipid metabolic process level 5: phospholipid metabolic process level 5: phospholipid biosynthetic process level 7: inner mitochondrial membrane organization level 7: mitochondrial respirasome assembly level 8: cardiolipin metabolic process level 8: mitochondrial ATP synthesis coupled electron transport level 9: cardiolipin acyl-chain remodeling
GO Terms: Molecular Function	level 3: transferase activity level 4: acyltransferase activity level 6: O-acyltransferase activity level 7: 1-acylglycerophosphocholine O-acyltransferase activity
GO Terms: Cellular Component	level 3: membrane level 4: mitochondrion level 5: mitochondrial membrane level 6: mitochondrial inner membrane level 6: mitochondrial outer membrane level 7: integral component of mitochondrial outer membrane
External source	Open in SGD