Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
COS7 Systematic Name
YDL248W Strain
S288c Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies External sources
Open in SGD
Open in KEGG
Gene Sequence
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>COS7 YDL248W
ATGAAAGAGAATGAAGTCAAAGATGAGAAAAGCGTAGATGTGTTATCCTTCAAACAGCTC
GAATCCCAAAAGATTGTTCTACCTCAAGATCTTTTCAGAAGCAGCTTTACCTGGTTTTGT
TATGAAATTTACAAGTCCTTAGCGTTTCGCATCTGGATGCTATTATGGCTACCACTTAGC
GTCTGGTGGAAACTTTCCAACAATTGTATTTACCCACTTATAGTTTCACTTCTGGTCCTG
TTTCTGGGACCAATATTTGTCCTTGTTATTTGTGGACTTTCTCGTAAGCGTTCCTTATCG
AAACAACTCATTCAGTTTTGCAAAGAGATTACTGAAAACACACCAAGTTCTGATCCTCAT
GATTGGGAAGTCGTTGTAGCAAATCTAAATTCGTACTTATATGAAAATAAGGCTTGGAAT
ACTAAGAATTTCTTTTTCAATGCTACGGATTGTGAGAAAATGTTCAGAACAACTGTTCTT
GAACCATTTTCTTTGAAAAAAGATAAAGCTGCCAAGGTTAAGTCATTTAAGGATTCTGTC
CCTTATATCGAAGAGGCTTTGCAAGTGTATGCTACAGGATTTGACAAACAGTGGAAGTTG
TTTATTACTGAAAAATCATGGAGCCCTGTTGGCCTGGAAGACGTTCAGCTTCCCAAGGAT
ATTCATCGGTCCAAGCTTACTTGGTTTTTAAAGCGGATTTTCACTATTTACTCTCTACCA
TTATGGCTTGCTTTTTTGAACTGTATCTGCGTGTCACAGCATTTTTGCCTTGCATTTCGT
ATCTTGTGTCCTGGATTGTTTTTCCTCATGATGGTGTGGCTTTTCCAAAATATGAGGACG
ACTGCTTTACTCGTGAAAATGGAACACAAGATGCAATTCTTGTTGACTATTATAAATGAG
CAAGAAAGTGGTGCGAATGGATGGGACGAAATTGCAAGGAAAATGAATAGGTACTTGTTT
GAGAAAAAAGCCTGGAAGAATGAAGAGTTTTTCTTCGACGGGATTGACTGTGAATGGTTT
TTTAGCCACTTCTTCTACCGCCTTCTATCTGCAAAGAAATCTATGTGGCTTTTACCATTG
AATGTGGAACTATGGCCATATATTAAAGAAGCGCAATTGTCCCGCAATGAAGAGTCTTTA
ATGAAGAAATGA Promoter Sequence
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>COS7 YDL248W
TCAATTTATATACACTTATGCCAATATTACAAAAAAATCACCACTAAAATCACCTAAACA
TAAAAATATTCTATTCTTCAACCATAATACATAAACACACTTAATTGCGTCTTAATACTA
TCATGGTATCATTAACTTAAAGTTCCTTAATATCGTCATACCACTATGCTCTATTCCATA
TATTGTAATATAACTGTACTCTATAGTCATACAGACGCTTTTACTTCACCCCATCTTCTC
ATACTATTGTCATAGAATCTCACACTGACGCATGATTAAAACGAATAATTTTTACTGTAA
GGGCTGCCATCCGCGCTCTATCCTTTTGTTTGCAATATTTATATACAGAATCTCAAAACA
AGCGGGAGAAGTGCTAATTACCCAGAGGTCATGCATGATCTGAGTACCACCGTACCTCTA
GGTTTTGCTTTGATCCGTTTTACAGTGACACCGAACATAAGGGGAAGCTATTGACATGGT
ATCGAAAGGTTGTCCACATTGGGAAGTAACTTGGTTCTATGAATCTTCATGTCAGATACG
TAGGACAGACTCTTTCCTGTGTAAATATTTGTGACAGCTACGTCTATTTTCTACTAGATG
TTTACACAGTTTTGTCACAGGAAATCTACGCTTAAAATATGTATTTCATTCAAGCGGTAA
CCGCTGTACGAGCAGTGACATTGCTGGTCGCACCTTAAATGTAAACCAACGTTACGGCAC
ACCGTGATGTACCCGCATTAAAGTTTTGTAAATTCGTTATTACGATTATTGAATTGGCTA
GATAGAAAACAGGAAATGAAATGGATACCCTTTTCGAATAGCTGAGTTTCTTTGCCTAAA
ATAGCCCAACATTGTTGCCCTTTTTCTATCACGAGGTTACTGAGCCATTGCATGAACGCG
CGCGCCTCGGCGGCTTTTTTTTCCTGCTGTATAAAAGCGAAAAGCCAGAAGTTACTATCT
CGAATAAAAAACCCCTCGAACTGCCATCTCACTACCGAAA
Chr coordinates
Chr IV from 1802-2953
