Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
VPS74 Systematic Name
YDR372C Alias
API1, MNN3 Strain
S288c Description
Golgi PI4K effector, PtdIns4P sensor, and retention receptor; interacts with glycosyltransferases, and in the PtdIns4P-bound state mediates retention of these enzymes in the Golgi; PtdIns4P sensor that limits PI4K signaling and regulates lipid homeostasis, interacting with the catalytic domain of Sac1p, the major PtdIns4P phosphatase, directing dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; contributes to telomere function; ortholog of human GOLPH3 External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>VPS74 YDR372C
ATGTCTACTTTACAACGTCGTAGAGTCAATAGGGCGGATTCTGGAGATACTTCCTCCATT
CATTCTTCTGCTAACAATACCAAAGGAGACAAAATCGCAAATATTGCTGTTGACGGGGAT
GATGACAATGGAACAAACAAAAAGATTGCATATGACCCAGAAGAATCGAAATTGAGAGAC
AACATCAATATCCCTACGTTAACGTTGATGGAAGAAGTCTTATTGATGGGCTTAAGAGAT
AGAGAAGGATATTTGTCGTTTTGGAATGATAGTATTTCATATGCTTTGCGTGGTTGTATA
ATTATAGAATTAGCGTTAAGAGGTAAAATCAGAATCTTAGATGATTCCGCCAGGAAAAGG
TTCGATCTTTCCGAAAGGTTGATTGAAGTTATTGACAGTTCCAAAACTGGGGAAGTTTTA
CTGGATGAAACTTTGCAATTGATGAAAAACGACGAACCTTTGTCAATTTCTAACTGGATT
GATCTTTTAAGTGGTGAAACATGGAACCTTTTAAAGATCAACTATCAATTGAAACAAGTA
AGGGAAAGATTGGCAAAAGGTTTGGTCGATAAAGGTGTATTGAGAACAGAAATGAAAAAT
TTCTTTTTGTTTGACATGGCGACACACCCCATTGCAGACGCCAGCTGCAAAGAAGCCATT
AAGCGCAGAGTACTTTCTGTACTCGTATCGAGGAACATGGAATTAAGTTACAATGAATAT
TTTCCGGAGACAACATCTTTCAAAATCATTAGAACTTTAGCTTTAATATGTGGATCATAT
GGGGCAAACGTATTGGAGAATGTCCTGACTACGTTGGAATATGAGAAGAGAGATAAGGCA
ATTAGTAGAGCTGAAGAAATAATGGCACAATTTTCGCAATACCCATTTGATTTAGAAAAG
GAAACTGAGTTAGGTGTCTCCGTTAATTTAAACAAGGAAGTTAAAGAAGAGATAGAAAAC
AATCCTGGTCATGATTTACAATTGGAAGTTATTGCTGGTGTATTTGAAGTCTTTTCAAGA
ATGGATATGCTATTATGA Promoter Sequence
Download FASTA
>VPS74 YDR372C
TTTTATAAACACTCGCCACAATGGTTAGCATTTCATCAAATGTAATATATCCATCATGGT
TCAAATCATAAAGTTCGAAAGCCCAGCTCAGTTTTTCCTCCAAAGTTCCTCTGGACGTTG
TACTCAAAACTGTGATAAACTCTTCAAAATGTATGAATCCATTGTTGTCTTTATCAAAAA
CTGTAAAAAGGTGATTAGCAAAATCTTCAGGAGAACCAAATGGAAAAAACTGTTTGTATA
TCTTAACAAAATCTTCCCTAGCTAGTTGGCCACTAGGGCAATCCCTCAAAAATCCTTTAT
GCCATTGCTGGATTTCTCTTCTATCAAAATAGGTGGATTGTTTCAAACATGTCAGGTCAT
CTTTGGAAAGCTTTGACGTCTTGGCTCCCATTTTTTTTTTGAATCAAAAACAGTTTTCAA
GCACAAAATAACTCTCGCCGATTCTTAAACTAGCAACAATTATAAAACAGGAGGTAATAT
CCCTAGTTCATCAGTTCAATCGTTGACAAATTAAACATTATTTCAGTACTCTATGGTATA
ATAATAAAAAATACACCGAAGAGTTACCCTTTTTTCGTTTTTAATGATCAATTCTGGCTC
ATTTTTTTACTTCCTGAGCAGTCAACTACTACTGAAAAAAAGAGGCTAATGGGTACGCAT
TTACCTAAAAACAATTAGATCCCTGCCTTGGATCGTAATCTTGTTTATCTATCCTTTTTG
GACATTGACATCTATTTGTGTCGCAGTTAATTGCTTTCTGGGTACGTTGACTTTTTCAGT
TCTATATCGGCCCGTTGCTTACTCTGTTCAACTCACTTATTCTTTTGTTTCGGTTTGGGC
TGCTGCATTTATAGATTAAAAATAAATTTCAAATTTCCACGCTAACAAATAGAGCTAAAT
TAGCAGTTTCATTGTTGGCTATATTTTCATTACAACTTTTGATCTGATAACGTAAAAGAA
TTCAAACAAAAACTATCTAAAAAAATACAAAGCAAAAATC
Chr coordinates
Chr IV from 1222149-1221112
