Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
DOT1 Systematic Name
YDR440W Alias
KMT4, PCH1 Strain
S288c Description
Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response; single DOT1 gene produces two Dot1p isoforms from alternative translation start sites as a result of leaky scanning by the ribosome External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>DOT1 YDR440W
ATGGGCGGTCAAGAAAGTATATCAAATAATAACTCAGACTCATTCATTATGTCGTCCCCC
AACTTAGACTCTCAGGAATCTTCAATATCACCTATTGATGAGAAGAAAGGCACCGATATG
CAAACCAAGTCGCTTTCAAGCTATTCTAAAGGTACGCTTCTCTCTAAGCAAGTACAAAAT
TTATTAGAAGAAGCTAATAAATACGATCCAATATATGGGTCATCTTTACCTCGAGGATTT
TTAAGAGATAGAAACACCAAGGGTAAGGATAATGGGTTGGTTCCGCTGGTGGAGAAGGTT
ATACCTCCCATTCACAAGAAAACCAATAATAGAAACACAAGGAAGAAGTCATCTACCACC
ACGAAGAAGGATGTAAAGAAGCCAAAAGCTGCAAAAGTAAAAGGAAAAAATGGCAGGACT
AACCATAAACATACCCCAATTTCAAAGCAAGAAATAGATACTGCACGAGAAAAAAAGCCA
TTGAAAAAAGGTCGGGCAAACAAGAAGAATGATCGCGATAGTCCTTCATCAACATTTGTT
GATTGGAATGGCCCGTGTCTACGGTTACAATATCCATTATTTGACATAGAGTACTTAAGA
TCACATGAAATATATTCTGGAACTCCTATACAATCCATTAGTTTAAGAACAAATTCTCCA
CAGCCAACGAGCTTGACATCAGATAACGACACTTCCTCAGTAACGACAGCAAAGTTGCAG
AGTATTTTATTTTCAAATTATATGGAAGAGTACAAAGTCGACTTCAAAAGGTCAACAGCC
ATTTATAATCCAATGAGTGAAATTGGTAAATTAATTGAATACAGCTGCCTGGTCTTTTTA
CCTTCACCTTATGCTGAACAATTGAAGGAAACTATACTACCGGACCTAAATGCATCATTT
GATAACTCTGACACGAAAGGTTTCGTGAATGCTATAAATTTATACAACAAAATGATTCGT
GAAATTCCTAGGCAAAGAATAATTGACCATTTAGAAACAATTGATAAAATTCCTCGTTCA
TTCATTCATGACTTCTTGCATATCGTCTATACCAGGAGTATCCATCCGCAGGCGAATAAA
TTGAAACATTACAAAGCATTCAGCAATTATGTTTATGGAGAACTTTTGCCCAATTTCCTA
TCTGATGTATATCAACAATGCCAGTTGAAGAAGGGTGACACTTTCATGGATCTCGGTTCG
GGAGTAGGTAATTGCGTAGTACAAGCTGCGTTGGAATGTGGATGTGCATTAAGCTTCGGA
TGTGAAATCATGGATGATGCTAGCGATTTAACTATACTGCAGTACGAGGAACTAAAGAAG
AGGTGTAAGTTATATGGGATGCGTTTGAACAACGTGGAGTTTTCATTGAAGAAAAGCTTT
GTGGACAATAACAGGGTCGCTGAACTAATTCCTCAGTGCGATGTTATCCTCGTAAATAAT
TTTTTATTTGATGAAGATTTGAATAAAAAAGTCGAAAAGATACTACAAACGGCAAAAGTT
GGATGTAAGATCATAAGTTTGAAAAGTTTAAGAAGCCTCACTTATCAGATCAACTTCTAC
AATGTTGAGAACATCTTCAATAGATTAAAGGTGCAAAGGTATGATCTTAAGGAGGATAGT
GTTTCATGGACGCATAGTGGCGGAGAGTATTATATATCAACAGTGATGGAGGATGTGGAC
GAAAGTTTATTCAGCCCTGCTGCAAGAGGTAGGAGGAACAGAGGTACGCCGGTGAAGTAT
ACCAGATGA Promoter Sequence
Download FASTA
>DOT1 YDR440W
TTTTAAACAATTCGAGTGAAGGCCATGCGCTTCTTGTAAGCTTTGTTAATGAATCTATCT
TTTAGTTAAAAACATTTCTTTCTTTATCCAATTGAATTATGCCATTCGATATTAAATACG
ACAACAGGAACACTGAAGAACGGGATACTCCCCCCCCCCCTTGTGAATGTGCTACAATAA
ACAGAATATCGCCACCCGGTCACTTCTTCTCTCCAATTCTTACTAAATTAGCGATAAATT
CTACCCTTTCCATAACTGGCCGTTCTTCTGCAAGAGAATTTTTCCTACTTGAATAGGCAT
ACTTGAATCTGAAAAGTAGTCATAGATAGTGAAGTCTGCTTTATTAATAAAATTCCAGGA
TGTACTCTTGGAGATCGAATCAAGTTCCTAGAAATCCTTTGAGAAAGAAGCGGTGAATAC
CCGTAGGTAGGATTTTTTCACGTAATTAAACCGCCTTATCTTATTTGTTGCCAGAAAACT
AGAGGATGGAATAAACATATTCCCTAATGGTGTGGCATTTACCTGTCTGTCTAGTTTCTG
TTAGTGCATTCCAATGTCAGCTGCTTCGCTACATTGTTTCCAATGAAAGCTTGTATTTTC
AGAGTCGAAAGCGTCGTCGCCTCTTTTTATGGATGAAAGAGCTCTGGCATGAATTTTCTC
TGTAGTGAAAAAATGTTACGGCTAAAGACCGTAGAGTGACTTTCTTTGTTTTTCTGTTCT
TGAATTTAGACACTTACTTCACAATAGTATAACAAGCCAGAAACTAAGTAATGATTTACG
TGCCATTTTTTTTAGCAATATATGCATAATCCTGCTGACGCCTTCGCACGCGTCAATGAA
AAGGGACATTGAAAAATCGACCGGTAAGTGCTTTCAATGAGATAAACATAATTCGAATAT
AGGGCATCTCGTCGTCTTAATTGCCTTGAAAAATAACTGAGGTCCTCATCAAGGAGGTCA
CCAGTAATTGTGCGCTTTGGTTACATTTTGTTGTACAGTA
Chr coordinates
Chr IV from 1342493-1344241
