Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SPO11 Systematic Name
YHL022C Strain
S288c Description
Meiosis-specific protein required for meiotic recombination; makes DNA double-strand breaks (DSB) during meiotic recombination, homolog pairing, and synaptonemal complex formation; role in meiotic DSB formation involves a topo-II-like transesterase mechanism; forms monotetrameric complex; covalently linked to DSBs through a 5'-phosphodiester bond between a catalytic tyrosine (Y135) and the DSB 5'- end; sequence similarity to a topo VI subunit from archaea, fission yeast rec12 and human SPO11 External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SPO11 YHL022C
ATGGCTTTGGAGGGATTGCGGAAAAAATATAAAACAAGGCAGGAATTGGTCAAAGCACTC
ACTCCTAAAAGACGGTCCATTCACTTGAACTCCAATGGTCACTCCAACGGAACTCCCTGT
TCAAACGCAGATGTTTTGGCTCATATTAAGCATTTCCTGTCATTGGCGGCTAATTCATTA
GAGCAACATCAACAGCCTATTTCAATCGTCTTTCAAAACAAAAAAAAAAAAGGCGATACA
AGCAGTCCTGACATTCACACAACATTGGACTTCCCTTTGAATGGCCCGCATCTATGCACT
CATCAGTTCAAGTTGAAAAGATGCGCAATCCTTTTAAACTTATTGAAAGTCGTTATGGAA
AAATTACCGCTAGGTAAAAACACTACAGTGAGAGATATCTTCTACTCCAACGTGGAATTG
TTTCAAAGACAAGCAAACGTAGTCCAGTGGCTGGACGTTATACGCTTTAATTTCAAGCTC
TCTCCAAGAAAATCCTTAAACATTATACCAGCTCAAAAGGGTTTAGTTTATTCGCCTTTC
CCCATTGATATTTATGACAATATTCTGACATGTGAAAATGAACCAAAGATGCAAAAGCAA
ACAATTTTCCCTGGTAAGCCCTGTCTAATTCCATTTTTCCAAGATGATGCGGTCATCAAG
TTAGGGACAACAAGTATGTGTAATATTGTAATAGTGGAAAAAGAAGCTGTCTTCACCAAA
TTAGTAAATAATTATCACAAGTTGAGTACAAATACCATGCTCATTACAGGTAAGGGATTT
CCAGATTTCTTGACAAGGTTATTCCTAAAAAAACTAGAACAATATTGCTCCAAATTGATA
TCGGACTGTTCTATATTTACCGATGCGGACCCCTATGGGATTAGCATAGCCCTAAATTAT
ACTCACTCGAATGAACGCAACGCTTATATTTGCACGATGGCAAACTATAAAGGAATTCGT
ATTACGCAAGTTTTGGCACAAAATAATGAAGTGCATAACAAATCCATTCAATTATTGAGT
TTGAATCAGCGCGACTACTCCTTAGCCAAGAATTTGATAGCATCTCTGACTGCCAACAGC
TGGGATATTGCAACTTCACCATTAAAGAACGTCATCATAGAATGTCAGCGGGAAATTTTT
TTCCAAAAGAAAGCTGAAATGAACGAGATTGATGCCAGAATTTTTGAATACAAATGA Promoter Sequence
Download FASTA
>SPO11 YHL022C
AATGCCCATTATGCCAATAAAGACTTGCCGCTACATACGGATTTACCATTTTTAGAAAAT
GTGCCAGGTTTCCAGATTCTACAATCTCTACCTGCTACAGAAGGGGAAGATCCCAATACT
AGACCCATGAATTACTTCGTGGACGCATTTTATGCTACCCGTAATGTTAGAGAATCGGAT
TTTGAGGCTTATGAGGCTTTACAAATTGTTCCTGTAAATTATATATATGAAAACGGCGAT
AAGAGGTACTACCAATCCAAACCTTTAATCGAACATCACGACATTAACGAGGACAATACT
CTTCTGGGTAATTATGAGGCCTTGATTAAATGCATTAACTACTCTCCACCATACCAAGCA
CCTTTCACTTTCGGAATTTATGATAAGCCCTCAGATCTAAATAATAATCTGGACTTGAAT
TTAATTACCACCCCAGCAAAACTAACAGAGAGATTTTTGTTTAAGTCTTTCATTAGGGGG
TTGAACTTGTTCGAGAGTCATATCAATGACTTCAACAATCAATTTAGATTGCAGTTGCCC
GAAAACTGTTGTGTTATCTTTAACAACAGGAGAATTTTGCATGCTAACTCTTTAACAAGC
TCAAACCAGCAATGGTTAAAGGGTTGCTATTTCGATTCTGATACTTTCAAGAGTAAATTA
AAGTTCTTGGAAGAGAAGTTTCCTCATGACAAATAACTTCATTTTTTCAGCATAGTTATG
TGATTCTTTATATTTATTTATTTTCTCTCTGTGTAGTGACAATTTTTTTTTTAATGTTTC
ATGTTAAATATATTTATTTTAAGAAGCCGTCAGTTTCCTTTTGTTTCATTGAAATCAATA
ACTAAAATTAAAATTATAAAAGGAATAACGTAAAAGAAAGTCTACTACCCAAGGAAAATC
TACTTTATTTAGTGATTATATCCAACTAAATATCATTCAAATAACCTCACATATTTGTCT
TCACCCTTAAGATTTTACGATTTACTAAGTTCACCTTCTC
Chr coordinates
Chr VIII from 64157-62961
