Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
LTO1 Systematic Name
YNL260C Strain
S288c Description
Substrate-specific adaptor protein involved in apo-Rli1p maturation; subunit of the Yae1-Lto1 complex, recruiting apo-Rli1p to the CIA targeting complex, facilitating the insertion of an Fe/S cluster by the Fe-S biosynthetic machinery; deca-GX3 motif crucial for complex formation; essential for aerobic but not anaerobic growth; homolog of human ORAOV1, which is overexpressed in solid tumors; co-expression of ORAOV1 and YAE1 homolog YAE1D1 restores growth and Rli1p maturation after LTO1 depletion External sources
Open in SGD
Open in KEGG
Gene Sequence
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>LTO1 YNL260C
ATGGATTTTGATAATTTACTAAACCTAGAAGAACAGTATTACCAAGAAGGTTTTCTGGAG
GGCCAGAATGAGAATATAAAGCAGAGCTTTCTAGAAGGTAAACAGTATGGTTTACAAGTG
GGATTCCAAAGATTTACGCTCCTGGGACAAATGGAAGGTTTGTGTGATGTTATAGAATCG
TATGGATTGCATAGTCCAACACTAGAAAAGAATATACATACCATTCGTACTTTAATGAAA
GGTTTGAAAATGAATAACGATGATGAAAGTGTGATGGAATTTGAGAGGGTGTTAATAAAA
TTGAAAAATAAGTTTAGAACCATTCTAATAACTCTTCATCGATTAGTTAAAGATAAAAGA
ACCCCCACCGTGACATTTGAAGTCTTTGAAGACGTTTCAAGGGCCATTGCCGGAGAAATT
AGAGGTTTTGTAGAAAATGAAGACATCGCAAAGAATAAGACAAAACAAAATCAGGCTCAA
TCCTGGTAA Promoter Sequence
Download FASTA
>LTO1 YNL260C
TACAATTATTAGCGAAGGAACCAAGTTACAAAAAGATGAGAGAAAAATTCGCCACTATGG
GCAAGTTTCTACCATTACATTTAAAGGAGATTATGGAGATGTTTTACAATGGGGATTTTT
ATCTTTTTGCGACAGACGAACTAATCCAATGGATAGAGTTATTGTTTGCCGACACTCCCC
TGCGAAGGAATGCCATTGATGATATTTACGAAATTAGAGGCACTGCTCTAGATGATTAAA
AAATAATTAATCGTAGGATAGGTTACATGATCATTGCAATAGATGTACATCTTGTATTAC
GTATGCGTAAGTTGTCTTTTTTTCAGTTTTCTAATAAATTTCACGTGATGCGGTAGTTTT
TTTTGGGGGTGCAAAGTTGGCACATCTTGTAGTGCATTTTTGAGCTTCTTAAATGACTTG
AATCATCTTAAAACATTGCAGGATGAGATTTCCAACGACACAAGAGAGAACTAGCGCAAA
AGATGGCAGAGATAAAACATTATCAATTCAATGTCGTCATGACCTGCTCGGGATGTTCTG
GTGCAGTCAATAAAGTTTTGACGAAATTAGAACCAGACGTTTCCAAAATAGATATATCCC
TTGAAAAGCAATTAGTAGATGTATATACTACACTTCCTTACGATTTTATTTTAGAAAAGA
TTAAGAAAACCGGAAAGGAAGTTAGATCTGGCAAACAATTGTGAATGAAAGTGAAGAGAA
ATAGTTTTTTACTCTATTTTGTATTGTAGCTACTTAAGTAAATGATTAATATTCTCAATA
GGATGCTTACGAAGAAAAAAGTCTTTTTTTATTGTTTTATTGTTTTATTCTTTGTTGGCT
ATGTAGCCATTTGCCTTTTCAGTATAATCTTACTAATATAAAAATCTCAATCATGGTGAG
AAATCGTTTTATAAGAAAAATGAAAAAAAACTTGTTTAAATCAAATCACTTATCATATTT
GAAGAGTAAATGGAAAGTAAAGATCACTGGACAAATAAAA
Chr coordinates
Chr XIV from 156859-157347
