Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HRD1 Systematic Name
YOL013C Alias
DER3 Strain
S288c Description
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) of misfolded proteins; upon autoubiquitination triggers retrotranslocation of misfolded proteins to cytosol for degradation; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; likely plays a general role in targeting proteins that persistently associate with and potentially obstruct the ER-localized translocon External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>HRD1 YOL013C
ATGGTGCCAGAAAATAGAAGGAAACAGTTGGCAATTTTTGTAGTTGTCACATATTTGCTC
ACATTTTATTGCGTGTATTCAGCCACCAAGACAAGCGTTTCCTTTTTGCAAGTAACACTG
AAGCTAAATGAAGGCTTCAATCTAATGGTTTTGTCGATATTCATCTTATTAAATTCTACC
TTACTATGGCAACTCCTAACGAAACTATTATTTGGTGAACTGAGGCTTATTGAGCATGAG
CACATTTTTGAAAGGTTACCATTTACCATTATAAACACCTTGTTTATGTCCTCACTGTTC
CACGAACGGTATTTTTTCACAGTGGCATTTTTTGGACTATTACTACTCTATCTGAAAGTT
TTCCATTGGATTTTAAAGGATAGGCTGGAGGCCTTATTACAGTCAATAAATGATTCCACC
ACAATGAAAACCCTTATCTTTAGTAGATTCTCATTTAACCTCGTACTATTGGCGGTTGTA
GACTACCAGATAATAACACGATGCATCTCCTCCATATATACAAACCAAAAGAGTGATATT
GAATCCACATCCCTTTACCTGATACAAGTAATGGAGTTTACCATGCTTTTGATTGATTTG
CTAAATTTATTCCTACAGACTTGTTTGAATTTCTGGGAATTTTATCGCTCACAACAAAGT
CTGTCTAATGAGAACAACCATATTGTCCATGGCGATCCTACAGATGAAAACACGGTTGAG
TCTGATCAATCTCAGCCAGTGCTGAATGACGACGACGATGACGACGATGATGATAGACAA
TTTACCGGCCTGGAGGGTAAATTCATGTATGAAAAAGCAATTGACGTATTCACAAGATTC
TTAAAAACGGCACTTCATTTGTCTATGCTAATACCATTTAGGATGCCTATGATGCTTTTG
AAAGATGTGGTGTGGGATATCTTGGCACTATATCAAAGTGGCACAAGTTTGTGGAAAATC
TGGAGAAATAACAAACAGCTCGACGACACTCTTGTCACTGTCACCGTAGAACAGCTACAA
AATTCTGCAAATGATGACAATATTTGTATCATTTGTATGGATGAGTTAATACATTCTCCA
AACCAGCAGACGTGGAAGAATAAAAACAAGAAACCCAAAAGGTTACCTTGTGGCCACATA
CTTCATTTGTCGTGTTTAAAGAATTGGATGGAACGTTCTCAGACTTGTCCTATTTGTAGA
TTGCCTGTCTTTGATGAAAAAGGTAATGTTGTGCAAACGACTTTCACTTCCAATAGTGAT
ATCACGACACAGACCACCGTAACAGATAGCACTGGGATAGCGACAGATCAACAAGGTTTC
GCAAACGAAGTAGATCTACTTCCCACAAGAACAACTTCCCCTGATATAAGGATAGTGCCT
ACTCAAAATATAGACACATTAGCAATGAGAACAAGGTCAACCTCTACACCATCTCCTACG
TGGTATACGTTCCCATTACATAAAACTGGTGATAATTCTGTTGGGTCAAGCCGATCAGCC
TACGAATTTTTGATCACAAATTCAGATGAGAAAGAAAATGGTATTCCTGTCAAATTAACA
ATAGAAAATCACGAAGTAAATTCTCTGCATGGAGACGGGGGCGAGCAAATTGCCAAGAAA
ATTGTCATACCAGATAAATTTATCCAGCATATCTAG Promoter Sequence
Download FASTA
>HRD1 YOL013C
ATCGTTAAATTCAATTTCGCACTATAGCCGCACGTAAAAATAACTTAACATAATGTCAGG
AAAAGCTCATGGAGGTAAAGGTAAATCCGGCGCTAAAGACAGTGGTTCATTGAGATCTCA
ATCTTCTTCAGCAAGGGCTGGCTTGCAGTTTCCTGTCGGTAGGATTAAGCGTTACCTGAA
AAGGCACGCTACCGGCCGAACAAGAGTAGGATCCAAAGCTGCCATTTATTTGACTGCTGT
GTTGGAATATTTGACTGCTGAAGTGCTGGAGTTGGCTGGTAATGCAGCCAAGGATCTTAA
AGTCAAGAGGATTACCCCAAGACATCTGCAATTGGCCATTAGAGGTGACGATGAGTTAGA
TTCTTTGATCAGGGCTACAATTGCTTCAGGTGGTGTTTTGCCTCATATAAATAAAGCATT
ATTATTGAAAGTGGAAAAAAAGGGAAGTAAGAAATAAGAAGAATAGTTTTTCTTTCCCAT
TTCCCGTAATTCTCCCTGCTCCTGTATCCTCATTCTATCCATATTAACGTCTGTATCATT
ATTATAAGTTGAAATTTGTCTCTCCGTACCCGAGTTATATACATACATATATGTAATCTA
TCTCTCCTTTCACGTCTAATCTCTTATGTTTTTACTATAATATATAGCATGAAAATATAC
TCTCACACAATATTCCCAACGATAGCGCAGTAGCCGTTATGTACGCAGAAATTTGGTCAG
GGCTTTCTTTTTGTTGAACTTTGCATACCCGGAAAAATGGAAATTAAGGACACCTACAAA
AGTACACTGTAGAAATCAAATCAAAGAAAAGGTTTAATAGACGATAAATTTCCATACGTG
CCGACAGGACAAAAAAAAAACCCCCCTACCATTTCTAATAACAGCTTCACCACTAGTTAT
ACTGTCGACTTTCTACCGATTTGTTGGTTCCTTTTTATAACCAGAAAATCATCTATCAAT
TGCAATTTGTAAGAGAAGGGGAGAAAGACAAAATAATAAT
Chr coordinates
Chr XV from 303035-301380
