Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PFY1 Systematic Name
YOR122C Alias
CLS5, PRF1, profilin Strain
S288c Description
Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PFY1 YOR122C
ATGTCTTGGCAAGCATACACTGATAACTTAATAGGAACCGGTAAAGTCGACAAAGCTGTC
ATCTACTCGAGAGCAGGTGACGCTGTTTGGGCTACTTCTGGTGGCCTATCTTTGCAACCA
AACGAAATTGGTGAAATTGTTCAAGGCTTCGACAATCCAGCTGGTTTGCAAAGCAATGGT
TTGCATATTCAAGGCCAAAAGTTCATGTTGTTGAGAGCTGACGATAGAAGTATCTACGGT
AGACATGATGCTGAGGGTGTTGTTTGTGTAAGAACTAAGCAAACCGTTATTATTGCTCAT
TATCCACCAACCGTACAAGCCGGTGAGGCCACCAAGATTGTCGAGCAATTGGCTGACTAC
TTGATTGGTGTTCAATACTAA Promoter Sequence
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>PFY1 YOR122C
TGTCTTTAAAGAATCAAATACACAAATAGTGCAGTGGTCAGACGGTACATATTCGCTAAA
AGTTGGTGAAGAGTGTACAGATATATTGGTCAACGATACGAGCAACACTTTTTTGACAGT
ATCGCATGACCAACAAGAGTTGATCCAGTGTTACGAAGGGGGTGAAATAAAAAAGACGTT
GATGTTTATTCCAACTTCGACGAATTCAAAAATACATCAAAAACTAAGTAAAGCTGTTAT
AAGAAGGAACCAAAGACAAAGCAAGGGTCCTGGAACATACATTGTAAGTATGGATCCTGA
AGTGGAAAAGAAGGAGTTAGAGAGAAAGCAAAGCCAGATTTTAAGAGACAGAAGGAGAAG
ACAGCTCAAAGAAAAGGAGAAACAAGAATCCCCAGATGCCGCTTTTGAGACGGGATTTAG
AAAGCAAAATTCACCCACTACCTATGGAGCCTCGAGAAGAAATGAATATGAAGAAGATGA
CTTTTTAGTCGACGACGATGAGGAAGAGGAGGCTGCGTTTGACGACGAAGAGGATGATAA
TGAGGAAGAAGAAGAAGAAGAGGACGCGGATGAAGAGAACGCCTCTCGTCTAAGAAATTT
AAAAAGAGAAGGAGCAGCAATGTACAGAGAAGAGGAAGAAGAAGAAAAAGATAGGAGCGA
GACAAAAAGAAGAAGGGTTGCGGTCATCGAGGACGACGAAGACGAGGATTAGAGGAGACG
TTACTTTGTTTATATATATTAGTATGTACAATCGCAAAGAAATGGAGTGATGACATGTTG
TAGTATTTAGTATGAGGTTACTGTGTGGGAGGTTTTACCATGATTTTTGGCGAGAACACG
CCATGAAATGTCTTTGTACGAAACTCATTACCCGCATTAATATTTTTTTTCTTTTTAAAG
CTCAGTTGACCCTTTCTCATTCCCTTCTTAAAACAACTGTGTGATCCTTGAGAAAAGATA
AATTACATACACAACATAAACCCAACTACGATCGCAAATT
Chr coordinates
Chr XV from 552665-552298,552887-552875
