S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Yrr1p	YBR037C	PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Negative	N/A	Carbon source quality/availability	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h	N/A
		PubMed Gallagher JE et al., Genes & development, 2014 Feb 15;28(4):409-21	Direct	ChIP-seq	N/A	S288c	Stress	YPD medium + 4NQO	N/A
		PubMed Wang X et al., Frontiers in microbiology, 2017;8():367	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Unstressed log-phase growth (control)	Cells harvested from 300 ml of culture (specific medium not clear) at an OD600 of 0.4. Transcription factor gene overexpression pAFT2-1up vs aft2Δ strain.	0.735603831761192
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Unstressed log-phase growth (control)	Yeast cells were grown in rich medium (YPD), to an A600 of 0.8–1.0.	-0.597616651627533
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Stress	Grown in SD medium until log phase (OD600 ≈ 1.6-2.0) at 30 ºC, in the presence of 5 mM vanillin (inhibitor). Transcription factor gene deletion.	0.735603831761192
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Unstressed log-phase growth (control)	Grown in SD medium until log phase (OD600 ≈ 1.6-2.0) at 30 ºC. Transcription factor gene deletion.	-0.597616651627533
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	Unstressed log-phase growth (control)	YPD medium, 25.C	N/A