S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Rap1p	YBR191W	PubMed Lieb JD et al., Nature genetics, 2001 Aug;28(4):327-34	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Lee TI et al., Science (New York, N.Y.), 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Unstressed log-phase growth (control)	Grown in complete synthetic medium (CSM) when selection was required, or in rich medium (YPD) at 30°C. Temperature shift experiment: exponentially growing yeast cells grown in YPD (A600 = 0.8 − 1.2) at 37°C for 1 h. Transcription factor gene deletion.	1.575659
		PubMed Kasahara K et al., Molecular and cellular biology, 2007 Oct;27(19):6686-705	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD	N/A
		PubMed Badis G et al., Molecular cell, 2008 Dec 26;32(6):878-87	Direct	ChIP	N/A	S288c	N/A	N/A	N/A
		PubMed Lavoie H et al., PLoS biology, 2010 Mar 9;8(3):e1000329	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	2.6730870420625
		PubMed Bondra ER et al., Proceedings of the National Academy of Sciences of the United States of America, 2023 Oct 3;120(40):e2304343120	Direct	ChIP - seq	N/A	W303	Unstressed log-phase growth (control)	YPD medium	N/A
		PubMed Buechel ER et al., FEBS letters, 2024 Jan;598(2):169-186	Direct	ChEC-seq2	N/A	BY4741	Unstressed log-phase growth (control)	Control	N/A
		PubMed Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47	Indirect	RNA-seq - wt vs TF overexpression	Negative	CEN.PK2-1D	Carbon source quality/availability	YPD medium (36h) (post-diauxic shift)	-1.17746124138243
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Negative	cen.pk-2-1C	Carbon source quality/availability	RNA extraction at 36h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	-2.26178412952021