S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Rph1p	YBR297W	PubMed Schroeder EA et al., Cell metabolism, 2013 Jun 4;17(6):954-964	Indirect	Microarray analysis - WT vs TF Deletion	Negative	DBY2006	Stress	24h men: Cultures grown in minimal dextrose medium supplemented with essential amino acids at 30°C, 200 rpm. Cells treated with 50 µM menadione during exponential growth (OD600 0.5 to 2.0). RNA harvested at 24 h (day 1 of chronological lifespan, post-diauxic/stationary phase).	-0.257649
		PubMed Shu WJ et al., Nucleic acids research, 2020 Sep 4;48(15):8360-8373	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Carbon source quality/availability	Ethanol medium - Overexpression media lacked leucine to ensure plasmid selection. The cultures grown for 70 h in ethanol medium were diluted twice with a fresh medium to ensure continuous growth.	0.378932455492982
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Nitrogen source quality/availability	Grown in YPD to OD600 of 0.8 at 30 ºC. Treated with rapamycin for 2h (100 nM). Transcription factor gene deletion.	0.378932455492982
		PubMed Fang W et al., Cell reports, 2022 Apr 12;39(2):110672	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	CEN.PK	Carbon source quality/availability	Yeast cells grown to log phase in YPL medium from 0.1 OD. Transcription factor gene deletion.	-0.294065167361371
		PubMed Glazier VE et al., mBio, 2023 Oct 31;14(5):e0152123	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Unstressed log-phase growth (control)	Cultured in minimal medium (1.7 g/L YNB, 5 g/L ammonium sulfate, 20 g/L glucose, 80 mg/L histidine, 80 mg/L methionine, 80 mg/L uracil and 240 mg/L leucine) with 200 rpm orbital shaking at 30°C, pH 5.5, until the mid-exponential phase (OD600 = 0.6). Transcription factor gene deletion.	1.4622279082286